P 156 Corneal sensitivity to chemical, mechanical and thermal stimuli in humans

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P 156 Corneal sensitivity to chemical, mechanical and thermal stimuli in humans

m To evaluate comeal sensitivity in 50% galactose-fed rats and explore its potential use in assessing diabetic keratopathy in this animal model. Mathods: Weanling male Sprague-DawleY rats were divided into two weight-matched groups and fed Purina laboratory chow (15001) plus 1) 50% alpha cellulose fiber (controls. n=9); or 2) 50% D-salactose (n= 12). Comeal sensitivity measurements were conduct...

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Human corneal adaptation to mechanical, cooling, and chemical stimuli.

PURPOSE To psychophysically investigate adaptation in human corneas using the Belmonte pneumatic esthesiometer. METHODS Twenty, 8, and 20 healthy subjects were enrolled in the mechanical, cool, and chemical experiments, respectively. Thresholds were estimated using an ascending method of limits and three intensities (subthreshold, threshold, and suprathreshold, in random order) were each pres...

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Corneal and conjunctival sensitivity to air stimuli.

AIMS To determine the repeatability of ocular surface sensitivity to mechanical stimulation using air stimuli and the effect of contact lens (CL) wear on sensitivity. METHODS Repeatability: 14 subjects (24-39 years) participated. Mechanical sensitivity to warmed (34 degrees C) and ambient (20 degrees C) air was measured for the central cornea (CC), inferior cornea (IC), and inferior conjuncti...

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Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.

Transient receptor potential (TRP) channels are polymodal signal detectors that respond to a wide array of physical and chemical stimuli, making them important components of sensory systems in both vertebrate and invertebrate organisms. Mammalian TRPA1 channels are activated by chemically reactive irritants, whereas snake and Drosophila TRPA1 orthologs are preferentially activated by heat. By c...

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P-156: Adolescent Pregnancy

Background: It is estimated that 15 million births occur every year to adolescents. This represents about 11%of all births each year. The global average rate of births per 1000 females aged 15-19 years is 65. A range of social, cultural, biological and service delivery factors contribute to the high levels of adolescent pregnancy and childbirth. This study was conducted to determine the causes ...

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ژورنال

عنوان ژورنال: Vision Research

سال: 1995

ISSN: 0042-6989

DOI: 10.1016/0042-6989(95)90472-7